Well you didn't ask what size, you asked how big can i go, lol!
The bigger the valve the higher rpm your power band will be.
I run 1 3/8 ports, which translates into a little under 1 1/2" intake valve.
1 1/4 exhaust port and a 1 5/16 valve on it.
And like Tommy said, its alot of work to get those in there!